Biolets – Random Sequence Generator
This is a small but useful Java based tool, for those who are interested in bio-sequence analysis. Biolets is a biological sequence generator using which DNA, RNA and Protein sequences can be generated. It incorporates various probability distribution functions for generating random numbers which are then mapped into either nucleotides or amino acids as per user selection. Third position control in codons, GC base pair control, Tandem repeats control and Supersede control are some of the features included in Bioloets.  There are options for users to set the percentages of purines, pyrimidines, nucleotides and amino acids in the sequence to be generated, type of the sequence to be generated etc. The feature which gives an edge to Bioloets over similar existing tools is the Energy calculation. This tool calculates the energy associated with the sequence generated using Gibbs free energy. This tool gives absolute control over nucleotides /amino acids to be generated. This tool can be the first member in a complete bio-sequence analysis suite. The range of applications of this tool can be from simple bio-sequence generation to synthetic biology like designing a bio-sequence according to your wish!
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